If you move the folder containing the sage directories (e.g. to a new server) you will need to edit each PC to point to the new location. Its helpful to know the directory locations before undertaking this! You will also need to re-enter the serial and activation code.
In c:\programdata\sage\payroll delete the files:
Re run sage and browse to the new directory location
As above but files are found in c:\program files\sage\payroll
Sage Line 50
Edit the company file found in c:\programdata